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  • Adriano dos Santos

Why to supplement with Glutamine?


Let's talk in wide spectrum about glutamine - which is one of the elements that makes up our approach. This nutritional component is part of the group of non-essential amino acids. But what does that mean? In principle, let us briefly clarify the function of amino acids. They are nutrients that combine to form proteins and are responsible for helping our body to perform vital functions such as developing, repairing tissues and improving cardiovascular health, neurological and intestinal function, among others. They can be framed in essential and nonessential. The essentials are those that we do not produce in our body, but we can extract them from food (like tryptophan and leucine). The non-essential ones, are synthesized by our organism, that is, we obtain from the consumption of other amino acids without it comes from the feeding. There are 11, glutamine is one of them.


Glutamine can be beneficial for intestinal health and, when necessary, also contribute to physical activity practitioners. However, it is common for people to refer glutamine to aspects such as gaining muscles (such as bodybuilders). Many professionals condemn the need for glutamine in the muscle building process because the necessary nutrient is already present in whey protein. (in the case of high-performance athletes). Note that in this context, glutamine may not really be needed, and in this regard, I totally agree.


But, now for those individuals in another context, who do not make daily use of whey for example and are far from aiming for muscle gain, the circumstance is another.


Understand that glutamine is far beyond that, of any need for protein, amino acids or muscle building. It may be well indicated if it is necessary to replace the intestinal mucosa. Especially in cases of gastritis, esophagitis, of absorbing syndromes such as leaky gut, irritable bowel syndrome, chron, and so many others.


We must be clear that its applicability must be directed in accordance with the organic context of each individual (which takes into account habits such as food, intestinal condition, physical activities or certain clinical circumstance that may demand the amino). The fact is that aminoacids play important roles on multiple fronts. They regulate gene expression, metabolic pathways, contribute to human development, and can also boost immunity. In addition, studies point to non-essential aminoacids, such as glutamine, as the main metabolic fuel for the small intestine. Scientific findings have shown that glutamine in the diet can act for the integrity of the intestinal mucosa. It acts in favor of cellular growth and helps in the absorption and transport of nutrients, as well as in the increase of intestinal permeability. It has the function of nourishing the enterocytes (cells of the intestine), ensuring that the mucosa of the gastrointestinal tract is strengthened and thus prevents the entry of bacteria and macromolecules into the bloodstream.


An intact gastrointestinal mucosa contributes to the absorption and utilization of nutrients. Glutamine is still a precursor of glutathione, an antioxidant that can protect the body against the production of free radicals.


Then you ask me, "Adriano. Can I take glutamine? "Let's understand some essential points before answering with an assertive (Yes / No).


First, supplementation is food supplement when necessary and according to individuality. The rule is real food as a source of health. Glutamine is an amino considered safe and its benefits are well described in this context. Ideally, you should always recognize your individual context. Therefore, the most important thing is to talk to your nutritionist (preferably a functional nutritionist) and understand your body and its specificity.


Glutamine has long been considered a beneficial nutrient, which supplies fuel for metabolism, regulating cell proliferation, repairing and maintaining the functions of the intestinal barrier.


But what does this have to do with gratitude and our mood?


The more closed the gut - the less bacteria will permeate - the more bacteria permeate increases the risk of irritation. The inflamed bowel can lead to irritation and moodiness.


The health of our intestinal microbiota can impact the central nervous system (CNS). Some bacteria in our intestinal flora (or absence of them) may impact our neurotransmitters, such as GABA, which is the main neurotransmitter inhibitor of the CNS and is significantly involved in the regulation of many physiological and psychological processes. Changes in central GABA receptor expression are implicated in the onset of anxiety and depression, which may be correlated with functional intestinal disorders. A gut with a strong protective barrier will boost GABA and will contribute to mood enhancement as well.


There are 4 pillars for a healthy life:

  • Healthy eating and bowel;

  • Sleep;

  • Exercise;

  • Body & mind & spirit balance!

One is intimately connected to the other, and its integration is vital. If you have been following already my programmes, I might have already introduced glutamine in your life.


Do you understand that the combination of lots of water and glutamine in your food habits, and plus gratitude goes far beyond words? The combination of these elements can have a positive impact on the balance of body, mind and spirit!


*Oncology patients should consult their oncologist and/or nutritionist before implementing it.


5 g or a teaspoon is an amount which can be used without any restrictions (more than this only with medical indication)


Enjoy the positive effect of glutamine in your physical and mental health.


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