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The Circadian Matrix™ Framework

Where precision medicine meets circadian science to restore your health

The Circadian Matrix Framework: Functional medicine & Nutrition meet Circadian Science to restore your health

The 
Circadian 
Matrix

Behind every sleepless night or drained morning is more than stress or bad habits — it’s your biology falling out of rhythm.
The Circadian Matrix™ is my clinical framework that brings together the best of precision medicine and circadian science to uncover those hidden imbalances and realign your body’s clocks.

By analysing your genetics, metabolism, hormones, microbiome, immune system, and environmental exposures, we identify where timing has gone astray. From there, we design a personalised roadmap that restores balance through nutrition, light, movement, resilience strategies, and targeted therapies.

This is where sleep — and health — stop being guesswork and become measurable, sustainable, and transformative.

The 
Circadian
Nutritionist Method

A consultation at AdS Vitality Studio in The Hague

The Circadian Nutritionist Method translates science into practice. It’s not a one-size-fits-all plan — it’s a personalised protocol that aligns your rhythms with optimal metabolic, digestive, and cognitive function.

​What sets this method apart is the integration of advanced lab testing as well as circadian analysis: microbiome analysis, hormone mapping, nutrient and metabolomic panels, genetic and epigenetic data, inflammatory markers, and circadian-specific tests such as dim light melatonin onset.

Instead of overwhelming to-do lists, you’ll receive clear priorities that create momentum. Progress is tracked with structured follow-ups, wearable or lab data, and iterative refinements, ensuring changes are both effective and lasting.

The Five Pillars of Transformation

The Core Pathways

The Health & Sleep Optimisation Approach analyses six interconnected pathways.

By mapping these pathways, we see where your rhythm is misaligned and how to bring it back into balance.

Genomics & Epigenetics: uncovering your clock genes and how lifestyle switches them on/off.

Metabolomics: blood sugar, energy pathways, and nutrient status across the 24-hour cycle.

Gut Microbiome: trillions of microbes that produce serotonin, melatonin, and SCFAs for sleep regulation.

Immune & Inflammatory Balance: circadian regulation of cytokines and overnight repair

Hormonal Rhythms: cortisol, melatonin, thyroid, reproductive hormones, and their daily timing

Detox & Environmental Stressors: liver and glymphatic night-time clearance, plus light, toxin, and digital exposures.

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Advanced Laboratory Integration

Generic advice doesn’t work. That’s why every Sleep Optimisation plan integrates advanced diagnostics:

  • Microbiome mapping (diversity, SCFA production, enterotypes).

  • Hormone profiling (melatonin, cortisol, reproductive hormones).

  • Nutrient & metabolomic panels (vitamin D, iron, glucose, HbA1c, lipids).

  • Genetic & epigenetic testing (including circadian gene variants).

  • Inflammatory & immune markers.

  • Circadian-specific tests: Dim Light Melatonin Onset (DLMO), actigraphy, wearable sleep and HRV data.

This gives us a measurable baseline, guiding precise interventions and allowing you to track progress over time.

Roadmap to Health Recovery
Your journey is structured, clear, and measurable:
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3. PERSONALIZED PROTOCOL

Nutrition timing, light exposure, movement, resilience strategies, and targeted nutraceuticals.

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5. LONG TERM RESILIENCE

Once aligned, your circadian system becomes a foundation for energy, recovery, and healthy ageing.

2. ADVANCED LAB & CIRCADIAN TESTING

Nutrition timing, light exposure, movement, resilience strategies, and targeted nutraceuticals.

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4. ONGOING SUPPORT & ITERATION

Nutrition timing, light exposure, movement, resilience strategies, and targeted nutraceuticals.

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1.CONSULTATIONS

A detailed health history to uncover triggers, mediators, and patterns. ​

Why Choose ADS Vitality for Health Optimisation?
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Research Backed
  • grounded in my published work on circadian rhythms, SCFAs, and gut–brain–sleep interactions.
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Precision Driven
  • no two programmes are the same; everything is tailored to your biology.
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Sustainable
  • designed to create long-lasting, measurable change.
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Your Biology is ready to Thrive
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