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The Circadian Matrix™ Framework

Where precision medicine meets circadian science to restore your health

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The 
Circadian 
Matrix

Behind every sleepless night or drained morning is more than stress or bad habits — it’s your biology falling out of rhythm.
The Circadian Matrix™ is my clinical framework that brings together the best of precision medicine and circadian science to uncover those hidden imbalances and realign your body’s clocks.
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By analysing your genetics, metabolism, hormones, microbiome, immune system, and environmental exposures, we identify where timing has gone astray. From there, we design a personalised roadmap that restores balance through nutrition, light, movement, resilience strategies, and targeted therapies.

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This is where sleep — and health — stop being guesswork and become measurable, sustainable, and transformative.

The 
Circadian
Nutritionist Method

A consultation at AdS Vitality Studio in The Hague

The Circadian Nutritionist Method translates science into practice. It’s not a one-size-fits-all plan — it’s a personalised protocol that aligns your rhythms with optimal metabolic, digestive, and cognitive function.

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​What sets this method apart is the integration of advanced lab testing as well as circadian analysis: microbiome analysis, hormone mapping, nutrient and metabolomic panels, genetic and epigenetic data, inflammatory markers, and circadian-specific tests such as dim light melatonin onset.

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Instead of overwhelming to-do lists, you’ll receive clear priorities that create momentum. Progress is tracked with structured follow-ups, wearable or lab data, and iterative refinements, ensuring changes are both effective and lasting.

The Five Pillars of Transformation

The Core Pathways

The Health & Sleep Optimisation Approach analyses six interconnected pathways.

By mapping these pathways, we see where your rhythm is misaligned and how to bring it back into balance.

Genomics & Epigenetics: uncovering your clock genes and how lifestyle switches them on/off.

Metabolomics: blood sugar, energy pathways, and nutrient status across the 24-hour cycle.

Gut Microbiome: trillions of microbes that produce serotonin, melatonin, and SCFAs for sleep regulation.

Immune & Inflammatory Balance: circadian regulation of cytokines and overnight repair

Hormonal Rhythms: cortisol, melatonin, thyroid, reproductive hormones, and their daily timing

Detox & Environmental Stressors: liver and glymphatic night-time clearance, plus light, toxin, and digital exposures.

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Advanced Laboratory Integration

Generic advice doesn’t work. That’s why every Sleep Optimisation plan integrates advanced diagnostics:

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  • Microbiome mapping (diversity, SCFA production, enterotypes).

  • Hormone profiling (melatonin, cortisol, reproductive hormones).

  • Nutrient & metabolomic panels (vitamin D, iron, glucose, HbA1c, lipids).

  • Genetic & epigenetic testing (including circadian gene variants).

  • Inflammatory & immune markers.

  • Circadian-specific tests: Dim Light Melatonin Onset (DLMO), actigraphy, wearable sleep and HRV data.​

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This gives us a measurable baseline, guiding precise interventions and allowing you to track progress over time.

Roadmap to Health Recovery
Your journey is structured, clear, and measurable:
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3. PERSONALIZED PROTOCOL

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Nutrition timing, light exposure, movement, resilience strategies, and targeted nutraceuticals.

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5. LONG TERM RESILIENCE

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Once aligned, your circadian system becomes a foundation for energy, recovery, and healthy ageing.

2. ADVANCED LAB & CIRCADIAN TESTING

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Nutrition timing, light exposure, movement, resilience strategies, and targeted nutraceuticals.

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4. ONGOING SUPPORT & ITERATION

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Nutrition timing, light exposure, movement, resilience strategies, and targeted nutraceuticals.

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1.CONSULTATIONS

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A detailed health history to uncover triggers, mediators, and patterns. ​

Why Choose ADS Vitality for Health Optimisation?
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Research Backed
  • grounded in my published work on circadian rhythms, SCFAs, and gut–brain–sleep interactions.
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Precision Driven
  • no two programmes are the same; everything is tailored to your biology.
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Sustainable
  • designed to create long-lasting, measurable change.
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Your Biology is ready to Thrive
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